Fact sheet

D-chiro-inositol (DCI) – a naturally occurring isomer of inositol, is an important component in all human cells. Inositol-containing lipids and phosphates are required for various structural and functional processes, including membrane formation, signalling and osmoregulation. D-chiro-inositol acts as a critical second messenger, mediating cellular responses to insulin. Studies demonstrate this compound plays a role in supporting ovarian and menstrual function, healthy glucose and insulin metabolism, lipid metabolism, and cardiovascular function. It may also help regulate inflammation metabolism and modulate serotonin activity.19, 20

D-chiro Inositol effectiveness in oocyte quality21

amount of oocytes retreived, pcs



Ovulatory effect of DCI

Ovulatory effect of DCI

Characteristics of 44 women with the Polycystic Ovary Syndrome at baseline and after the Administration of D-Chiro-Inositol or Placebo for six to eight weeks.

John E. Nestler et al. Ovulatory and metabolic effects of d -chiro-inositol in the polycystic ovary syndrome. The New England Journal of Medicine, 1999.

Useful references:

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